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are allergic to sildenafil, as contained in VIAGRA and Revatio®, or any of the substances in VIAGRAConsequences of Other Medicine on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (big route) and CYP2C9 (slight route). As a result, inhibitors of those isoenzymes may perhaps lessen sildenafil clearance and inducers of those isoenzym